Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

SARS-CoV-2 Spike protein was predicted by molecular docking to bind the host cell surface GRP78, which was suggested as a putative good molecular target to inhibit Covid-19. We aimed to confirm that GRP78 gene expression was increased in blood of SARS-CoV-2 (+) versus SARS-CoV-2 (−) pneumonia patien...

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Библиографические подробности
Опубликовано в: :Pharmaceuticals (Basel)
Главные авторы: Palmeira, Andreia, Sousa, Emília, Köseler, Aylin, Sabirli, Ramazan, Gören, Tarık, Türkçüer, İbrahim, Kurt, Özgür, Pinto, Madalena M., Vasconcelos, M. Helena
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345920/
https://ncbi.nlm.nih.gov/pubmed/32630514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13060132
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