Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins

Iron is an essential element for various physiological processes, but its levels must remain tightly regulated to avoid cellular damage. Similarly, iron plays a dual role in systemic inflammation, such as with sepsis. Leukocytes utilize iron to produce reactive oxygen species (ROS) to kill bacteria,...

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Bibliographic Details
Published in:Antibiotics (Basel)
Main Authors: Fokam, Danielle, Dickson, Kayle, Kamali, Kiyana, Holbein, Bruce, Colp, Patricia, Stueck, Ashley, Zhou, Juan, Lehmann, Christian
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345558/
https://ncbi.nlm.nih.gov/pubmed/32466384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9060283
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