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Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus
Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic b...
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| Publié dans: | Antibiotics (Basel) |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7345174/ https://ncbi.nlm.nih.gov/pubmed/32526926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9060313 |
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