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Javamide-II Inhibits IL-6 without Significant Impact on TNF-alpha and IL-1beta in Macrophage-Like Cells

The main aim of this study is to find a therapeutic compound to inhibit IL-6, not TNF-alpha and IL-1beta, in macrophage-like cells, because the high-levels of IL-6 production by macrophages are reported to cause unfavorable outcomes under several disease conditions (e.g., autoimmune diseases, and ac...

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Publicat a:Biomedicines
Autors principals: Park, Jae B., Peters, Renee, Pham, Quynhchi, Wang, Thomas T. Y.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344767/
https://ncbi.nlm.nih.gov/pubmed/32485858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8060138
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