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Synergistic Effect of WTC-Particulate Matter and Lysophosphatidic Acid Exposure and the Role of RAGE: In-Vitro and Translational Assessment

World Trade Center particulate matter (WTC-PM)-exposed firefighters with metabolic syndrome (MetSyn) have a higher risk of WTC lung injury (WTC-LI). Since macrophages are crucial innate pulmonary mediators, we investigated WTC-PM/lysophosphatidic acid (LPA) co-exposure in macrophages. LPA, a low-den...

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Publicat a:Int J Environ Res Public Health
Autors principals: Lam, Rachel, Haider, Syed H., Crowley, George, Caraher, Erin J., Ostrofsky, Dean F., Talusan, Angela, Kwon, Sophia, Prezant, David J., Wang, Yuyan, Liu, Mengling, Nolan, Anna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344461/
https://ncbi.nlm.nih.gov/pubmed/32560330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph17124318
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