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Functions and Clinical Significance of Super-Enhancers in Bone-Related Diseases

Super-enhancers (SEs) are a large cluster of cis-regulatory DNA elements that contain many binding motifs, which master transcription factors and cofactors bind to with high density. SEs usually regulate the expression of genes that can control the cell identity and fate, and SEs can be used to expl...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Qu, Jian, Ouyang, Zhanbo, Wu, Wenqiang, Li, Guohua, Wang, Jiaojiao, Lu, Qiong, Li, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344144/
https://ncbi.nlm.nih.gov/pubmed/32714929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00534
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