Aberrant DNA methylation levels of the formyl peptide receptor 1/2/3 genes are associated with obstructive sleep apnea and its clinical phenotypes

Background: FPR1 over-expression and insufficiency of FPR2 and FPR3 are associated with disease severity of obstructive sleep apnea (OSA). We hypothesized that epigenetic modification of the FPR1/2/3 genes may underlie intermittent hypoxia with re-oxygenation (IHR) injury in OSA. Methods: DNA methyl...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Chen, Yung-Che, Huang, Kuo-Tung, Su, Mao-Chang, Hsu, Po-Yuan, Chin, Chien-Hung, Lin, I-Chun, Liou, Chia-Wei, Wang, Ting-Ya, Lin, Yong-Yong, Hsiao, Chang-Chun, Lin, Meng-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344102/
https://ncbi.nlm.nih.gov/pubmed/32655788
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