Conjugation of arginylglycylaspartic acid to human serum albumin decreases the tumor-targeting effect of albumin by hindering its secreted protein acidic and rich in cysteine-mediated accumulation in tumors

Human serum albumin (HSA) accumulates in tumors by the enhanced permeability and retention (EPR) effect, which is a passive targeting effect in tumors. A recent study showed that secreted protein acidic and rich in cysteine (SPARC), an albumin-binding protein, mediates albumin accumulation in tumors...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Transl Res
Κύριοι συγγραφείς: Park, Cho Rong, Song, Myung Geun, Park, Ji-Yong, Youn, Hyewon, Chung, June-Key, Jeong, Jae Min, Lee, Yun-Sang, Cheon, Gi Jeong, Kang, Keon Wook
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: e-Century Publishing Corporation 2020
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344055/
https://ncbi.nlm.nih.gov/pubmed/32655786
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