Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia

Autologous T cells engineered to express a chimeric antigen receptor (CAR) against the CD19 antigen are in the frontline of contemporary hemato-oncology therapies, leading to high remission rates in B-cell malignancies. Although effective, major obstacles involve the complex and costly individualize...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Rozenbaum, Meir, Meir, Amilia, Aharony, Yarden, Itzhaki, Orit, Schachter, Jacob, Bank, Ilan, Jacoby, Elad, Besser, Michal J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343910/
https://ncbi.nlm.nih.gov/pubmed/32714329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01347
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