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The development of the dog heartworm is highly sensitive to sterols which activate the orthologue of the nuclear receptor DAF-12

Prevention therapy against Dirofilaria immitis in companion animals is currently threatened by the emergence of isolates resistant to macrocyclic lactone anthelmintics. Understanding the control over developmental processes in D. immitis is important for elucidating new approaches to heartworm contr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Long, Thavy, Alberich, Mélanie, André, François, Menez, Cécile, Prichard, Roger K., Lespine, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343802/
https://ncbi.nlm.nih.gov/pubmed/32641726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67466-9
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