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Preclinical Evaluation and Dosimetry of [(111)In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1)

PURPOSE: Endosialin/tumor endothelial marker-1 (TEM1) is an attractive theranostic target expressed by the microenvironment of a wide range of tumors, as well as by sarcoma and neuroblastoma cells. We report on the radiolabeling and preclinical evaluation of the scFv78-Fc, a fully human TEM1-targeti...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Cicone, Francesco, Denoël, Thibaut, Gnesin, Silvano, Riggi, Nicolo, Irving, Melita, Jakka, Gopinadh, Schaefer, Niklaus, Viertl, David, Coukos, George, Prior, John O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343747/
https://ncbi.nlm.nih.gov/pubmed/31993928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01479-8
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