Tyrosine phosphorylation of the myosin regulatory light chain controls non-muscle myosin II assembly and function in migrating cells

Active non-muscle myosin II (NMII) enables migratory cell polarization and controls dynamic cellular processes, such as focal adhesion formation and turnover, and cell division. Filament assembly and force generation depend on NMII activation through the phosphorylation of Ser19 of the regulatory li...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Biol
Main Authors: Aguilar-Cuenca, Rocío, Llorente-González, Clara, Chapman, Jessica R., Talayero, Vanessa C., Garrido-Casado, Marina, Delgado-Arévalo, Cristina, Millán-Salanova, María, Shabanowitz, Jeffrey, Hunt, Donald F., Sellers, James R., Heissler, Sarah M., Vicente-Manzanares, Miguel
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343590/
https://ncbi.nlm.nih.gov/pubmed/32502416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.04.057
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