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Hybrid Magnetic Nanovectors Promote Selective Glioblastoma Cell Death through a Combined Effect of Lysosomal Membrane Permeabilization and Chemotherapy

[Image: see text] Glioblastoma multiforme is the most aggressive brain tumor, due to its high invasiveness and genetic heterogeneity. Moreover, the blood–brain barrier prevents many drugs from reaching a therapeutic concentration at the tumor site, and most of the chemotherapeutics lack in specifici...

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Bibliografiske detaljer
Udgivet i:ACS Appl Mater Interfaces
Main Authors: Pucci, Carlotta, De Pasquale, Daniele, Marino, Attilio, Martinelli, Chiara, Lauciello, Simone, Ciofani, Gianni
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343532/
https://ncbi.nlm.nih.gov/pubmed/32459082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.0c05556
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