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ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants

The Apolipoprotein E (APOE) e4 allele is associated with reduced longevity and increased Coronary Artery Disease (CAD) and Alzheimer’s disease, with e4e4 having markedly larger effect sizes than e3e4. The e2 longevity promoting variant is less studied. We conducted a phenome-wide association study o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Kuo, Chia-Ling, Pilling, Luke C., Atkins, Janice L., Kuchel, George A., Melzer, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343499/
https://ncbi.nlm.nih.gov/pubmed/32511104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103405
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