PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation

Chronic allograft dysfunction (CAD) resulting from fibrosis is the major limiting factor for long-term survival of lung transplant patients. Myofibroblasts promote fibrosis in multiple organs, including the lungs. In this study, we identified PLK1 as a promoter of myofibroblast differentiation and i...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yu, Jizhang, Xu, Heng, Cui, Jikai, Chen, Shanshan, Zhang, Hao, Zou, Yanqiang, Zhao, Jing, Le, Sheng, Jiang, Lang, Chen, Zhang, Liu, Hao, Zhang, Dan, Xia, Jiahong, Wu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343459/
https://ncbi.nlm.nih.gov/pubmed/32541091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103330
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