Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson’s disease (PD). Previous work showed that developmental dieldrin exposure increased neuronal susceptibility to MPTP toxicity in male C57BL/6mice, possibly via cha...

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Dades bibliogràfiques
Publicat a:Neurobiol Dis
Autors principals: Gezer, Aysegul O., Kochmanski, Joseph, VanOeveren, Sarah E., Cole-Strauss, Allyson, Kemp, Christopher J, Patterson, Joseph R., Miller, Kathryn M., Kuhn, Nathan C., Herman, Danielle E., McIntire, Alyssa, Lipton, Jack W., Luk, Kelvin C., Fleming, Sheila M., Sortwell, Caryl E., Bernstein, Alison I.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343230/
https://ncbi.nlm.nih.gov/pubmed/32422283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104947
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