Influence of Human Cytomegalovirus Glycoprotein O Polymorphism on the Inhibitory Effect of Soluble Forms of Trimer- and Pentamer-Specific Entry Receptors

Human cytomegalovirus (HCMV) envelope glycoprotein complexes, gH/gL/gO trimer and gH/gL/UL128-131 pentamer, are important for cell-free HCMV entry. While soluble NRP2-Fc (sNRP2-Fc) interferes with epithelial/endothelial cell entry through UL128, soluble platelet-derived growth factor receptor α-Fc (...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Brait, Nadja, Stögerer, Tanja, Kalser, Julia, Adler, Barbara, Kunz, Ines, Benesch, Max, Kropff, Barbara, Mach, Michael, Puchhammer-Stöckl, Elisabeth, Görzer, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343208/
https://ncbi.nlm.nih.gov/pubmed/32350071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00107-20
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