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雷帕霉素对重型再生障碍性贫血模型小鼠脾脏CD4(+)CD25(+) T细胞凋亡的影响

OBJECTIVE: To explore the effects and possible mechanism of rapamycin (RAPA) on apoptosis of CD4(+)CD25(+) Tregs from the mouse severe aplastic anemia (SAA) model. METHODS: The BALB/c female SAA model mice were induced by interferon-gamma in combination with busulphan. The SAA model mice were intrap...

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Detalhes bibliográficos
Publicado no:Zhonghua Xue Ye Xue Za Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial office of Chinese Journal of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342986/
https://ncbi.nlm.nih.gov/pubmed/29562463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.03.005
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