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RNA腺苷脱氨酶在MLL-AF9诱导的小鼠急性髓系白血病发病中的作用
OBJECTIVE: To establish the ADAR1 (adenosine deaminase that act on RNA 1) knockout MLL-AF9 acute myeloid leukemia (AML) mouse model, and to preliminarily investigate the effects of ADAR1 deletion on the development of AML. METHODS: The lineage(−)(Lin(−)) cells of ER-CreADAR1(lox/lox) mice and their...
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| Publicado no: | Zhonghua Xue Ye Xue Za Zhi |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Editorial office of Chinese Journal of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7342600/ https://ncbi.nlm.nih.gov/pubmed/26031523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2015.05.006 |
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