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新酪氨酸激酶抑制剂BGJ398对白血病细胞株KG-1细胞的抑制效应研究

OBJECTIVE: To explore the effects and possible mechanisms of the novel pan-FGFR inhibitor BGJ398 on KG-1 cells in vitro. METHODS: Effects of BGJ398 on cells proliferation were detected by CCK-8, the apoptosis was assessed by Annexin V-FITC. Reverse transcriptionquantitative polymerase chain reaction...

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Detalhes bibliográficos
Publicado no:Zhonghua Xue Ye Xue Za Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial office of Chinese Journal of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342572/
https://ncbi.nlm.nih.gov/pubmed/29562450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.02.013
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