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Engineering Thermo-pH Dual Responsive Hydrogel for Enhanced Tumor Accumulation, Penetration, and Chemo-Protein Combination Therapy

PURPOSE: Combined chemotherapeutic drug and protein drug has been a widely employed strategy for tumor treatment. To realize both tumor accumulation and deep tumor penetration for drugs with different pharmacokinetics, we propose a structure-transformable, thermo-pH dual responsive co-delivery syste...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Pang, Xiuping, Liang, Shuang, Wang, Tianqi, Yu, Shuangjiang, Yang, Rui, Hou, Teng, Liu, Yongjun, He, Chaoliang, Zhang, Na
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342477/
https://ncbi.nlm.nih.gov/pubmed/32753862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S253990
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