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Jurkat细胞SFRP基因甲基化及去甲基化诱导凋亡的研究

OBJECTIVE: To study the promoter methylation status of SFRP genes and the effect of 5-aza-2′-deoxycytidine (5-Aza-CdR) induced apoptosis via Wnt/β-catenin pathway by demethylation in Jurkat cells. METHODS: Jurkat cells were treated with different concentrations of 5-Aza-CdR. The cell proliferation l...

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Publicat a:Zhonghua Xue Ye Xue Za Zhi
Format: Artigo
Idioma:Inglês
Publicat: Editorial office of Chinese Journal of Hematology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342293/
https://ncbi.nlm.nih.gov/pubmed/26876254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.01.010
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