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腺病毒介导的SD-HA对K562细胞增殖抑制和凋亡诱导的作用机制

OBJECTIVE: To investigate whether fusion protein SD-HA could regulate its downstream signaling molecule activity by competing with the phospho-BCR-ABL Y177 site, and its mechanisms to inhibit proliferation and induce apoptosis of K562 cells. METHODS: Co-immunoprecipitation interaction technology ana...

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Bibliographic Details
Published in:Zhonghua Xue Ye Xue Za Zhi
Format: Artigo
Language:Inglês
Published: Editorial office of Chinese Journal of Hematology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342126/
https://ncbi.nlm.nih.gov/pubmed/29779329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2018.04.012
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