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Effects of G-protein mutations on skin color
A new class of dominant dark skin (Dsk) mutations discovered in a screen of ~30,000 mice is caused by increased dermal melanin. We identified three of four such mutations as hypermorphic alleles of Gnaq and Gna11, which encode widely expressed Gαq subunits, act in an additive and quantitative manner...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7341985/ https://ncbi.nlm.nih.gov/pubmed/15322542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1412 |
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