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Complexities of Understanding Function from CKD-Associated DNA Variants
Genome-wide association studies (GWASs) have facilitated the unbiased discovery of hundreds of genomic loci associated with CKD and kidney function. The vast majority of disease-associated DNA variants are noncoding. Those that are causal in CKD pathogenesis likely modulate transcription of target g...
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| Pubblicato in: | Clin J Am Soc Nephrol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7341770/ https://ncbi.nlm.nih.gov/pubmed/32513823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.15771219 |
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