Mitochondrial GWAS and association of nuclear – mitochondrial epistasis with BMI in T1DM patients

BACKGROUND: BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. METHODS: We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI. We identified additive interactions between mitoc...

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Detalles Bibliográficos
Publicado en:BMC Med Genomics
Main Authors: Ludwig-Słomczyńska, Agnieszka H., Seweryn, Michał T., Kapusta, Przemysław, Pitera, Ewelina, Handelman, Samuel K., Mantaj, Urszula, Cyganek, Katarzyna, Gutaj, Paweł, Dobrucka, Łucja, Wender-Ożegowska, Ewa, Małecki, Maciej T., Wołkow, Paweł P.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341625/
https://ncbi.nlm.nih.gov/pubmed/32635923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00752-7
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