Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation

BACKGROUND: Sepsis is an infection-induced aggressive and life-threatening organ dysfunction with high morbidity and mortality worldwide. Infection-associated inflammation and coagulation promote the progression of adverse outcomes in sepsis. Here, we report that phospho-Tyr705 of STAT3 (pY-STAT3),...

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Publicado en:Cell Commun Signal
Autores principales: Xu, Shunyao, Pan, Xiaojun, Mao, Lingjie, Pan, Hao, Xu, Wenwei, Hu, Yufeng, Yu, Xueshu, Chen, Zhiqiang, Qian, Songzan, Ye, Yincai, Huang, Yueyue, Pan, Jingye
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341624/
https://ncbi.nlm.nih.gov/pubmed/32641132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00603-z
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