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Clinical efficacy and safety in patients treated with teicoplanin with a target trough concentration of 20 μg/mL using a regimen of 12 mg/kg for five doses within the initial 3 days

BACKGROUND: A trough concentration (C(min)) ≥20 μg/mL of teicoplanin is recommended for the treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections. However, sufficient clinical evidence to support the efficacy of this target C(min) has not been obtained. Even though the r...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Ueda, Takashi, Takesue, Yoshio, Nakajima, Kazuhiko, Ichiki, Kaoru, Ishikawa, Kaori, Takai, Yoshiko, Yamada, Kumiko, Tsuchida, Toshie, Otani, Naruhito, Takahashi, Yoshiko, Ishihara, Mika, Takubo, Shingo, Ikeuchi, Hiroki, Uchino, Motoi, Kimura, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341468/
https://ncbi.nlm.nih.gov/pubmed/32641110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00424-3
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