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The Ancestral Caenorhabditis elegans Cuticle Suppresses rol-1

Genetic background commonly modifies the effects of mutations. We discovered that worms mutant for the canonical rol-1 gene, identified by Brenner in 1974, do not roll in the genetic background of the wild strain CB4856. Using linkage mapping, association analysis and gene editing, we determined tha...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Noble, Luke M., Miah, Asif, Kaur, Taniya, Rockman, Matthew V.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341120/
https://ncbi.nlm.nih.gov/pubmed/32423919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401336
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