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Overcoming Compensatory Mechanisms toward Chronic Drug Administration to Ensure Long-Term, Sustainable Beneficial Effects

Chronic administration of drugs leads to the activation of compensatory mechanisms that may inhibit some of their activity and induce unwanted toxicity. These mechanisms are an obstacle for maintaining a sustainable effect for many chronic medications. Pathways that adapt to the burden induced by ch...

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Foilsithe in:Mol Ther Methods Clin Dev
Príomhúdar: Ilan, Yaron
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341037/
https://ncbi.nlm.nih.gov/pubmed/32671136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.06.006
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