Prevention of Avian Retrovirus Infection in Chickens Using CRISPR-Cas9 Delivered by Marek’s Disease Virus

Reticuloendotheliosis virus (REV) is an avian retrovirus that causes an oncogenic, immunosuppressive, and runting-stunting syndrome in avian hosts. The co-infection of REV and Marek’s disease virus (MDV), an oncogenic herpesvirus in chickens, further increases disease severity and reduces MDV vaccin...

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Li, Kai, Liu, Yongzhen, Xu, Zengkun, Zhang, Yu, Yao, Yongxiu, Nair, Venugopal, Liu, Changjun, Zhang, Yanping, Gao, Yulong, Qi, Xiaole, Cui, Hongyu, Gao, Li, Wang, Xiaomei
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340974/
https://ncbi.nlm.nih.gov/pubmed/32650233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.06.009
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