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Increased EZH2 Levels in Anterior Cingulate Cortex Microglia Aggravate Neuropathic Pain by Inhibiting Autophagy Following Brachial Plexus Avulsion in Rats

After brachial plexus avulsion (BPA), microglia induce inflammation, initiating and maintaining neuropathic pain. EZH2 (enhancer of zeste homolog 2) has been implicated in inflammation and neuropathic pain, but the mechanisms by which it regulates neuropathic pain remain unclear. Here, we found that...

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Bibliografische gegevens
Gepubliceerd in:Neurosci Bull
Hoofdauteurs: Meng, Xiang-Lei, Fu, Pengfei, Wang, Lin, Yang, Xun, Hong, Guanghui, Zhao, Xin, Lao, Jie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Singapore 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340721/
https://ncbi.nlm.nih.gov/pubmed/32346844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00502-w
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