Evolution of Placental Invasion and Cancer Metastasis are Causally Linked

Among mammals, placental invasion is correlated with vulnerability to malignancy. Animals with more invasive placentation (e.g. humans) are more vulnerable to malignancy. To explain this correlation, we propose the hypothesis of Evolved Levels of Invasibility: the evolution of invasibility of stroma...

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Gepubliceerd in:Nat Ecol Evol
Hoofdauteurs: Kz, Kshitiz, Afzal, Junaid, Maziarz, Jamie D., Hamidzadeh, Archer, Liang, Cong, Erkenbrack, Eric M., Nam, Hong, Haeger, Jan-Dirk, Pfarrer, Christiane, Hoang, Thomas, Ott, Troy, Spencer, Thomas, Pavlicev, Mihaela, Antczak, Douglas F., Levchenko, Andre, Wagner, Günter P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340496/
https://ncbi.nlm.nih.gov/pubmed/31768023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-019-1046-4
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