P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases

Shortage of oxygen and nutrients in the brain induces the release of glutamate and ATP that can cause excitotoxicity and contribute to neuronal and glial damage. Our understanding of the mechanisms of ATP release and toxicity in cerebrovascular diseases is incomplete. This review aims at summarizing...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Cisneros-Mejorado, Abraham J., Pérez-Samartín, Alberto, Domercq, María, Arellano, Rogelio O., Gottlieb, Miroslav, Koch-Nolte, Friedrich, Matute, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340211/
https://ncbi.nlm.nih.gov/pubmed/32714144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00092
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