TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma

BACKGROUND: Tumor-associated microglia and macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs) are potent immunosuppressors in the glioma tumor microenvironment (TME). Their infiltration is associated with tumor grade, progression, and therapy resistance. Specific tools for image-guided...

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Vydáno v:Neuro Oncol
Hlavní autoři: Zinnhardt, Bastian, Müther, Michael, Roll, Wolfgang, Backhaus, Philipp, Jeibmann, Astrid, Foray, Claudia, Barca, Cristina, Döring, Christian, Tavitian, Bertrand, Dollé, Frédéric, Weckesser, Matthias, Winkeler, Alexandra, Hermann, Sven, Wagner, Stefan, Wiendl, Heinz, Stummer, Walter, Jacobs, Andreas H, Schäfers, Michael, Grauer, Oliver M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Neuroimaging
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339888/
https://ncbi.nlm.nih.gov/pubmed/32047908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa023
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