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A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission
The ESCRT complexes drive membrane scission in HIV-1 release, autophagosome closure, MVB biogenesis, cytokinesis, and other cell processes. ESCRT-I is the most upstream complex and bridges the system to HIV-1 Gag in virus release. The crystal structure of the headpiece of human ESCRT-I comprising TS...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7339825/ https://ncbi.nlm.nih.gov/pubmed/32424346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0426-4 |
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