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Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas
Radiotherapy is the cornerstone of treatment of high-grade gliomas (HGGs). It eradicates tumor cells by inducing oxidative stress and subsequent DNA damage. Unfortunately, almost all HGGs recur locally within several months secondary to radioresistance with intricate molecular mechanisms. Therefore,...
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| Publicat a: | J Exp Clin Cancer Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7339573/ https://ncbi.nlm.nih.gov/pubmed/32631383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01639-2 |
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