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QSAR-derived affinity fingerprints (part 2): modeling performance for potency prediction

Affinity fingerprints report the activity of small molecules across a set of assays, and thus permit to gather information about the bioactivities of structurally dissimilar compounds, where models based on chemical structure alone are often limited, and model complex biological endpoints, such as h...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Cortés-Ciriano, Isidro, Škuta, Ctibor, Bender, Andreas, Svozil, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339533/
https://ncbi.nlm.nih.gov/pubmed/33431016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-020-00444-5
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