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CircRNA CDR1as/miR-641/HOXA9 pathway regulated stemness contributes to cisplatin resistance in non-small cell lung cancer (NSCLC)

BACKGROUND: Cisplatin (DDP) is the first-line chemotherapeutic drug for non-small cell lung cancer (NSCLC), and long-term DDP stimulation increased resistance of NSCLC cells to this drug by enriching cancer stem cells (CSCs), which contributed to recurrence and worse prognosis of NSCLC, but the mole...

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Publicado en:Cancer Cell Int
Autores principales: Zhao, Yongsheng, Zheng, Renyan, Chen, Jian, Ning, Dong
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339514/
https://ncbi.nlm.nih.gov/pubmed/32655321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01390-w
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