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miR-205/RunX2 axis negatively regulates CD44(+)/CD24(-) breast cancer stem cell activity

Breast Cancer stem cells (BCSCs) have been extensively studied and have been used directly as a therapeutic target, but how the BCSCs themselves are regulated remain unclear. Here we reported identification of miR-205 that may act as a tumor suppressor and negatively-regulate BCSCs stemness and tumo...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Zhang, Lu, Liu, Lei, Xu, Xiaodan, He, Xiaogang, Wang, Gang, Fan, Chulin, Zheng, Qiping, Li, Feifei
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339278/
https://ncbi.nlm.nih.gov/pubmed/32642297
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