Metabolic and OXPHOS Activities Quantified by Temporal ex vivo Analysis Display Patient-Specific Metabolic Vulnerabilities in Human Breast Cancers

Research on mitochondrial metabolism and respiration are rapidly developing areas, however, efficient and widely accepted methods for studying these in solid tumors are still missing. Here, we developed a new method without isotope tracing to quantitate time dependent mitochondrial citrate efflux in...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Koit, Andre, Timohhina, Natalja, Truu, Laura, Chekulayev, Vladimir, Gudlawar, Shivakumar, Shevchuk, Igor, Lepik, Katrin, Mallo, Lea, Kutner, Riina, Valvere, Vahur, Kaambre, Tuuli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339107/
https://ncbi.nlm.nih.gov/pubmed/32695682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01053
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