Metabolic and OXPHOS Activities Quantified by Temporal ex vivo Analysis Display Patient-Specific Metabolic Vulnerabilities in Human Breast Cancers

Research on mitochondrial metabolism and respiration are rapidly developing areas, however, efficient and widely accepted methods for studying these in solid tumors are still missing. Here, we developed a new method without isotope tracing to quantitate time dependent mitochondrial citrate efflux in...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Koit, Andre, Timohhina, Natalja, Truu, Laura, Chekulayev, Vladimir, Gudlawar, Shivakumar, Shevchuk, Igor, Lepik, Katrin, Mallo, Lea, Kutner, Riina, Valvere, Vahur, Kaambre, Tuuli
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339107/
https://ncbi.nlm.nih.gov/pubmed/32695682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01053
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