Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer

The addition of bevacizumab to chemotherapy has prolonged overall and progression-free survival rates for metastatic colorectal cancer (mCRC). However, KRAS-mutant (KRAS-mut) CRC, lacking an ideal targeted agent, represents an inferior-response subgroup of patients. In the present study, we investig...

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Bibliografiske detaljer
Udgivet i:Neoplasia
Main Authors: Zhong, Longhui, Wang, Rong, Wang, Yanxia, Peng, Shunli, Ma, Yueyun, Ding, Sijie, Yang, Hong, Chen, Shiyu, Luo, Xiaoqing, Wang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339053/
https://ncbi.nlm.nih.gov/pubmed/32629177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.06.001
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