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Tmub1 Suppresses Hepatocellular Carcinoma by Promoting the Ubiquitination of ΔNp63 Isoforms

Transmembrane and ubiquitin-like domain-containing 1 (Tmub1) inhibits hepatocyte proliferation during liver regeneration, but its role in hepatocellular carcinoma (HCC) has yet to be revealed. In this study, we show that the levels of Tmub1 were significantly lower in HCC tissues and cells than they...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Fu, Hangwei, Zhang, Yida, Chen, Junying, Zhou, Bo, Chen, Geng, Chen, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338996/
https://ncbi.nlm.nih.gov/pubmed/32671188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.06.005
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