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11g, a Potent Antifungal Candidate, Enhances Candida albicans Immunogenicity by Unmasking β-Glucan in Fungal Cell Wall

In the course of optimizing GPI biosynthesis inhibitors, we designed and synthetized a 2-aminonicotinamide derivative named 11g. After evaluating the antifungal activity of compound 11g in vitro, we investigated the influences of 11g on fungi immunogenicity. In addition, we also took advantage of mu...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Huang, Xin, Liu, Yu, Ni, Tingjunhong, Li, Liping, Yan, Lan, An, Maomao, Zhang, Dazhi, Jiang, Yuanying
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338940/
https://ncbi.nlm.nih.gov/pubmed/32695076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01324
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