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Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance

Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the mechanisms responsible are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex interactions between tumor growth, immune system activation, and therapy-medi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tran, Anh Phong, Ali Al-Radhawi, M., Kareva, Irina, Wu, Junjie, Waxman, David J., Sontag, Eduardo D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338613/
https://ncbi.nlm.nih.gov/pubmed/32695118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01376
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