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The cellular heat shock response monitored by chemical exchange saturation transfer MRI

CEST-MRI of the rNOE signal has been demonstrated in vitro to be closely linked to the protein conformational state. As the detectability of denaturation and aggregation processes on a physiologically relevant scale in living organisms has yet to be verified, the aim of this study was to perform hea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kleimaier, Dennis, Goerke, Steffen, Nies, Cordula, Zaiss, Moritz, Kunz, Patrick, Bachert, Peter, Ladd, Mark E., Gottwald, Eric, Schad, Lothar R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338423/
https://ncbi.nlm.nih.gov/pubmed/32632120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68022-1
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