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FMR1 locus isoforms: potential biomarker candidates in fragile X-associated tremor/ataxia syndrome (FXTAS)

Fragile X associated tremor/ataxia syndrome (FXTAS) is a late adult-onset neurodegenerative disorder that affects movement and cognition in male and female carriers of a premutation allele of 55–200 CGG repeats in the Fragile X mental retardation (FMR1) gene. It is currently unknown if and when an i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zafarullah, Marwa, Tang, Hiu-Tung, Durbin-Johnson, Blythe, Fourie, Emily, Hessl, David, Rivera, Susan M., Tassone, Flora
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338407/
https://ncbi.nlm.nih.gov/pubmed/32632326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67946-y
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