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Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway

The Wingless-type protein 7a (Wnt7a) plays an antiproliferative role in non-small-cell lung cancer (NSCLC). Previous studies have indicated that Wnt7a expression was downregulated in radiation-resistant NSCLC cells. However, little is known about its biological functions and molecular mechanisms in...

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Détails bibliographiques
Publié dans:Biol Open
Auteurs principaux: Ai, Pingping, Xu, Xianhua, Xu, Shijie, Wei, Zhixia, Tan, Shun, Li, Junzhe
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338269/
https://ncbi.nlm.nih.gov/pubmed/32554486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.050575
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