Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium

Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. Ciliary dysfunction causes severe diseases, termed ciliopathies. Analyzing ciliary...

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Udgivet i:eLife
Main Authors: Hansen, Jan N, Kaiser, Fabian, Klausen, Christina, Stüven, Birthe, Chong, Raymond, Bönigk, Wolfgang, Mick, David U, Möglich, Andreas, Jurisch-Yaksi, Nathalie, Schmidt, Florian I, Wachten, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338050/
https://ncbi.nlm.nih.gov/pubmed/32579112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57907
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