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Lead-seq: transcriptome-wide structure probing in vivo using lead(II) ions

The dynamic conformation of RNA molecules within living cells is key to their function. Recent advances in probing the RNA structurome in vivo, including the use of SHAPE (Selective 2′-Hydroxyl Acylation analyzed by Primer Extension) or kethoxal reagents or DMS (dimethyl sulfate), provided unprecede...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Twittenhoff, Christian, Brandenburg, Vivian B, Righetti, Francesco, Nuss, Aaron M, Mosig, Axel, Dersch, Petra, Narberhaus, Franz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337928/
https://ncbi.nlm.nih.gov/pubmed/32463449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa404
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