Lead-seq: transcriptome-wide structure probing in vivo using lead(II) ions

The dynamic conformation of RNA molecules within living cells is key to their function. Recent advances in probing the RNA structurome in vivo, including the use of SHAPE (Selective 2′-Hydroxyl Acylation analyzed by Primer Extension) or kethoxal reagents or DMS (dimethyl sulfate), provided unprecede...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Twittenhoff, Christian, Brandenburg, Vivian B, Righetti, Francesco, Nuss, Aaron M, Mosig, Axel, Dersch, Petra, Narberhaus, Franz
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337928/
https://ncbi.nlm.nih.gov/pubmed/32463449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa404
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